Typically, doctors will want to see one or two follicles in the 18-20mm range at the time of trigger. Follicles Needed for an IUI or Gonadotropins Cycle. Multiple ovulation, or hyperovulation, occurs when both ovaries release an egg or when more than one egg is released by an ovary (it can be either ovary). The stimulation must result in a minimum of 3 mature (or close to mature) follicles (we consider follicles to be mature if they are 16-20mm in average diameter on the day of HCG). If you have two follicles, you could conceive twins. Mommapandax2 13/01/20. After last years blighted ovum, I'm really nervous but cautiously excited. Yes, your chances are higher for twins with 2 mature follies, but since our chances, being "infertile", are lower anyway, the increase still doesn't make it VERY LIKELY. Hi, i am 38. my amh is 1.3 fsh is 13.29 follicle size is 16-17mm two tubes are blocked took akt-2 nd clomaid50. 2. 07/14/2011 11:30 . So in theory, 3 follicles could create more than 3 babies!!! Only one follicle was fertilized or implanted. These results in double ovulation and the birth of non-identical twins. However, we were warned that there's always the chance that an egg splits into a set of identical twins, and that can happen to an egg that's already a fraternal twin or triplet. ovulation). Clomid - 3 Follicles - what would you do? This pregnancy, I had 4 mature follicles and I have one healthy baby boy. The stimulation must result in a minimum of 3 mature (or close to mature) follicles (we consider follicles to be mature if they are 16-20mm in average diameter on the day of HCG). I have unexplained fertility problems and my REI recommended Letrozole. I have a very intense fear of twins and am afraid to start meds that will increase my odds of twins. We are. Alternatively, if there are 2 follicles 16-20mm and at least 2 more that are 13-15mm, we can proceed to the egg retrieval. Subject: IUI with 5 good follicles. Hi Girls! There's only one way this can happen: multiple ovulation, AKA hyperovulation. He said the idea that you should move on if you don't get pregnant on the first one or two is "not true"--he believes chances are equal on each attempt. It's your choice. The good news is, last time I only had 1 mature follicle and 1 that was almost mature - this time I had 1 @ 18 and 2 over 20!!! My doctor suspects one of my immature follicles contained a mature egg because my triplets implanted far apart from each other so it's unlikely any combo of the 3 were identical. 2 mature follicles. Hello, With two mature follicles, your chances of having twins is about 32%. As with Clomid, ideally, you only want one or two follicles to grow to maturity. The good news is, last time I only had 1 mature follicle and 1 that was almost mature - this time I had 1 @ 18 and 2 over 20!!! The probability of each egg being fertilized and implanted is still around 30% each. Two mature follicles after a round of letrozole. In women younger than 38, raising the number of mature follicles at IUI from 1 to 5 was associated with an increase in clinical pregnancy rates from 14.6% to 21.9% (adjusted odds ratio, 1.6), primarily due to an increase in multiple gestations per cycle from 0.6% to 6.5% (aOR, 9.9). Your body thinks your follicles are not producing enough estrogen, so it starts producing more of the hormones that help the follicles mature so that they will start producing more estrogen. I have unexplained fertility problems and my REI recommended Letrozole. Babydust to all ttc. When learning about female reproduction, most people are taught that a woman's cycle is 28 days on average and that ovulation occurs at the mid-point, on day 14. An important factor is if you're MFI. When I did IVF I had 9 leading follicles and had the trigger shot and got 16 eggs, so yeah they should both release. If you have two follicles, you could conceive twins. These 2 weeks are going to take FOREVER Ovulation might occur on day 14 of your cycle. Triplets or more occur in less than 1% of IUI cycles. I have 6 mature follicles and had a trigger shot last night and my RE is not at all concerned about multiples, even though he said there is a chance. Hello, Even when there are 2 or more mature follicles in a cycle, the chances of a twin pregnancy is only around 4-8%. Follicle number. 1,113. If you have two . Fraternal twins result when two different eggs are fertilized, each by a different sperm cell. But it's possible. A Verified Doctor answered Obstetrics & Gynecology 35 years experience DH and I are open to twins (3+ is pretty scary though, lol), as twins run in my family so . I had two mature follicles at my ultrasoud this morning, and my reproductive endocrinologist told me that I had a good chance of getting pregnant and a 5% chance that it would be twins. 135, No. Most twins conceived with Clomid will not be identical. The probability of having twins in a natural pregnancy is approximately 1.1%, while the percentage of having identical twins naturally is 0.4%. A recently published study in Obstetrics and Gynecology (Vol. Instead of releasing just one egg at ovulation, the ovaries may release two or more. Ideally, a follicle should be between 16-22 mm in size. Harrisap, even with multiple follicles, I believe your chances of twins increases only by 10% or 11%, some studies even say it only increases by 8%. Anonymous. I've had 3 or 4 IUI's and none of them took, I had atleast 2 follicles each time. I'll say your chances of conceiving twins are fair, some people on clomid can produce 5 or more mature follicles and only conceive a singleton and some still get a bfn. Everyone was shocked it worked. To me, that's nothing. Every mature sized follicle could release an egg, and that egg could become fertilized. There was little increase in singleton pregnancies per IUI (14.1-16.4%) regardless of mature follicle number. Having more than that may not increase your chances of getting pregnant, but it can raise your chance of having twins or multiples. With 5 mature follicles, the per IUI twin and higher order multiple risk increased from 0.1% to 2.5% (aOR 12.5, 95%CI 1.4-108.7) . But…it also might not. Follicles on Letrozole / Femara. Hubby by and I have been ttc for almost 2 years. While there is no definitive evidence regarding the exact number of follicles that increases the risk of a multiple pregnancy, most providers exhibit caution with 3 or more mature follicles. Had an ultrasound done today .. doctor said I should be ovulating between 4-5 days and have 2 mature follicles .. high chance of twins ???? I have a very intense fear of twins and am afraid to start meds that will increase my odds of twins. Good luck and dont worry about it. When I had my trigger shot, I had two mature, one on each side. Clomid increases your odds of conceiving twins because your ovaries may ovulate more than one egg. Can anyone help me to understand: 1. Likes Received: 475. With the ovidrel shot, the chances of both the follicles rupturing is more. No. We were explained all the risks/chances of multiples and decided after 2 years of trying we'd just give it a go. So, although there is a chance that you may have twins, I do not think that you should abstain from this cycle. If you're using intrauterine insemination -IUI (sperms are placed directly in your uterus to fertilize your egg) and you are less than 40, having one or two mature follicles is preferred. Likelier, sure. Question: Previously I have had 3 children that are 12, 11, . We now have 2 month old fraternal twins girls they were born at 37 weeks and, despite low birth weight, are perfectly healthy, happy little babies. Ovulation doesn't guarantee pregnancy. Good luck! Or, you might not conceive at all. 5, May 2020), "Mature Follicle Count and Multiple Gestation Risk Based on Patient Age in Intrauterine Insemination Cycles with Ovarian Stimulation" (Evans et al) evaluated the risk of multiple level pregnancies by age group and the number of mature follicles obtained related to the use of COH-IUI treatment. At this juncture, based on the information provided by you, I can guide you this much. He says it's about 5% chance that I conceive trips. We are now preggo with twins from FET. This does increase your chances of twins. TTC2Long said: ↑. Having more may not significantly increase your chances of getting pregnant, but it does raise your risk of having twins or multiples if you do get pregnant, one study found. In women younger than age 38 years with more . Follicle monitoring, which involves several internal ultrasounds in the lead-up to ovulation, will show how many mature follicles you are producing. Follicle number. The heat can kill the sperm. I just wanted to you add you need a follicle size of 18mm and an e2 of 200 per follicle to indicate a mature follicle inside with even a chance of it having a good egg inside. Or you might conceive one baby. I would go for it, but we transferred two this time so I'm not opposed to twins. What Are The Chances Of Conceiving Twins While Having Two Mature Follicles? They let me proceed because the chances of success depend on so many factors -- your age, male factor, estradiol level. Extra body fat leads to increased levels of estrogen, and higher levels of estrogen can lead to overstimulation of the ovaries. Currently pregnant with twins from an injectibles+IUI cycle with 2 dominant follicles- except that I initially conceived triplets. After rebound OC, some women have rested ovaries working with double force, which can lead to the appearance of two dominant follicles, one in each ovary. Like. Does two follicles mean twins? Likelihood of a singleton pregnancy per IUI rose modestly . This can happen when a woman produces several eggs (most often two) at the same time. ! Follicles on Letrozole / Femara. I have a question about the number of mature follicles. I had a follicle study on CD 13 and had 2 mature follicles (21.21mm on left ovary and 21.84mm on right ovary) and a healthy lining of 12.64mm. The nurse told me that there was a chance of twins but I am going crazy because I cant do a home PG test until Oct 23rd. 2nd cycle dose doubled to 5.mg 3-7 -and it resulted in one mature follicle measuring 18mm.. It is possible to retrieve mature eggs from follicles smaller than 16 mm, but it is less likely. On the ultrasound diagnostic, it looks as if the dominant follicle is not developing - the persistence of the follicle. Once 2-3 follicles have reached this size, we will administer a trigger shot to induce oocyte maturation. Is that likely? It's like any other . My doctor never talked about reducing the follicles, They said 4 was the max they would go forward with, but the chance of them all taking was less than 1% So I went forward with it. The Dr. recommends waiting until next cycle so they can lower the dose to only have one or two mature follicles, so I don't run the risk of triplets. Ovulating as early as day 6 or 7 or as late as day 19 or 20 isn't uncommon or abnormal. Identical twins come from one egg— not two. If both the follicles rupture, there is a possibility of both of them getting fertilized resulting into a twin pregnancy. The risk of twins you were quoted from using Letrozole. What are the chances of having twins with 2 follicles? This is my first cycle on clomid 50 mg. Was told 2 days ago I have 3 mature follicles. When fraternal twins are conceived naturally (without fertility treatments), it's because two eggs were fertilized by sperm in a single menstrual cycle. Subsequent IUIs with 2-3 follies didn't work. Hello everyone, I am new to this forum. After last years blighted ovum, I'm really nervous but cautiously excited. I had two mature follies and he was a singleton. : Hey everyone, I need to talk this through and see what your opinions are. The role of LH changes over your cycle. Alternatively, if there are 2 follicles 16-20mm and at least 2 more that are 13-15mm, we can proceed to the egg retrieval. It is important to note that IDENTICAL twins come from one egg that splits, so multiple follicles are not an issue there. This is the purpose of . Of course, at this point I'm really hoping we get a real BFP in 2 weeks and that it implants correctly. If you're using intrauterine insemination (IUI) and you're under the age of 40, one or two mature follicles is preferred. Of course, at this point I'm really hoping we get a real BFP in 2 weeks and that it implants correctly. 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